Tübingen: PhD student (f/m/d) in Natural Sciences

Department of Internal Medicine, KKE Translational Immunology, index number 6340

Part-time
65 %

Limited:
36 months

Start of work:
as soon as possible

Application deadline:
03.07.2025

Tasks

• Conduct molecular biology techniques (e.g., cloning, PCR, gel electrophoresis)
• Produce and characterize novel antibody constructs using cell culture-based methods
• Perform functional in vitro assays (e.g., flow cytometry, ELISA, multiplex assays) to assess the efficacy and safety of antibody constructs, focusing on T cell activation, proliferation as well as tumor cell lysis
• Carry out in vivo studies in xenogeneic and syngeneic mouse models to evaluate the efficacy and safety of therapeutic antibodies

Profile

• Master's degree (or equivalent) in molecular biology, immunology, biotechnology, biochemistry, life sciences or related discipline
• Hands-on experience in immune / cellular biology and a strong background in immunology is an advantage
• Strong interest in immunology, cancer biology and translational research
• Familiarity with mouse models (FELASA B) and / or willingness to work with animals
• High level of motivation, independent work style, organizational, communication and team skills and fluency in written and spoken English

Benefits

• Work in the diverse environment of a modern university hospital, which, in addition to patient care, also focuses on medical research and teaching
• Future-proof job and location, as well as attractive remuneration including a company pension plan (VBL), with the greatest possible flexibility in working hours
• Subsidy for public transport tickets and attractive discounts on our employee service platforms
• Structured onboarding phase, hospital-owned academy for developing professional, social, and methodological skills
• Preventive health care through a wide range of sports activities

About us

The University Hospital of Tübingen is a leading center of German university medicine. Every year, around 75,000 inpatients and around 380,000 outpatients are treated. With around 10,600 employees, it is the largest employer in the region. The quality of patient care is certified with the KTQ seal of approval.

About CCU Translational Immunology

The CCU Translational Immunology, headed by Prof. Dr. Helmut Salih, focuses on research in the field of tumor immunology with the ultimate goal to develop novel immunotherapeutic strategies until the stage of clinical evaluation. Current projects focus on the development and preclinical characterization of novel advanced antibody constructs for the treatment of malignancies, with an emphasis on mobilization of T cells.